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Small-Scale Question Sunday for October 27, 2024

Do you have a dumb question that you're kind of embarrassed to ask in the main thread? Is there something you're just not sure about?

This is your opportunity to ask questions. No question too simple or too silly.

Culture war topics are accepted, and proposals for a better intro post are appreciated.

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The specific example is interesting. I don't notice a damn thing from NSAIDs for pain that can reasonably be assumed to be inflammatory, and IIRC they're indistinguishable from placebo for osteoarthritis pain.

Like I said pain is complicated, likewise pharm is complicated - some people are fast metabolizers of certain medication and get no effect at all.

Personally I find NSAIDs to be even better for low dose opiates for pain associated with significant inflammation (for me).