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Assuming that these are not rival empirical claims that can be investigated, yes.
I don't know. I've seen several trans skeptical people bite the bullet on trans suicide rates.
The attitude seems to either be "the threat of trans kids committing suicide is emotional blackmail meant to shut down the argument from society and parents and force them to go through with mutilating their child against their will" or occasionally even "if they commit suicide at higher rates, then completely ignoring the issue solves the issue (through the self-removal of trans people from the population.)"
I mean, there's nothing stopping both claims from being true (to the extent they're empirically testable.) It could hypothetically be that social contagion and permissive doctors are allowing large numbers of cis children to ruin their bodies through transition followed by inevitable detransition, and that from a purely medical perspective the most effective way to prevent the suicide of enduringly trans children is to allow them to socially transition and take puberty blockers until adulthood when they can make the choice of whether to undergo hormonal therapy and cosmetic surgery. In that hypothetical world, the difficulty would be with separating cis children from trans children in a reliable way that minimized overall harm to both groups.
The empirical case can only solve so much without models of what is happening. The DSM-V's intro talks about how it models mental disorders, and it basically says that they are useful perspectives for treatment and not necessarily a single "real" disease with a known cause or set of causes. That is, ADHD is "real" to doctors using the DSM to the extent that it has been found that patients coming in complaining about a common cluster of issues, tend to have those issues resolved through a common cluster of treatments. And it's no different for gender dysphoria. When it comes to a gender dysphoria diagnosis today, there is no need for brain tests or an "intersex brain" hypothesis or anything more empirical than, "have they had 2 out of these 6 listed symptoms for at least 6 months?"
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