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The workers themselves are the main problem. They constantly violate the bio sphere containment area, and they themselves are a biological entity.
I think it is difficult sticking to lengthy isolation periods and being good about cleanliness on a long term consistent basis. Hospitals do their best to accomplish this, but I don't think any hospital would ever claim 100% effectiveness. And that is the real problem. A bio testing location working on dangerous pathogens needs to be 100% effective at preventing bio sample escape. A single escape and its all over. All of the "value" of that lab is gone and far into the negative if they cause a Covid level problem. Covid caused trillions in damage, so just for any of these labs to be worth it they need to be safe 99.9999% of the time (expected damage multiplied by likelihood of causing the damage), which measured in days means about a million days without incident, and that is basically 100%.
It's insane that any GoF research is allowed in the first place. Those jokers aren't even doing it to create new vaccines? There's plenty of already extant dangerous pathogens they could be working on creating vaccines against, yet they'd rather have the thrill of creating "the most dangerous virus ever, bro!" There have been leaked emails to that effect. From the group of people who, when COVID started, agreed it very likely came from a lab, and then agreed to state the exact opposite, that it didn't come from the lab, to the public.
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I certainly agree, anyone involved in GOF research deserves to catch Ebola in the first place, the risk to reward ratio could serve as a space elevator!
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