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Notes -
"Deaths of despair" are confounded by increased use of opioids on an outpatient basis and the subsequent crackdown (leading addicts to substitute more dangerous alternatives), followed by the fentanyl boom.
Also, the other ideas OP mentioned are confounded by mental health care becoming more fashionable, greater awareness, greater access to mental health care due to increases in income, changes in insurance coverage, etc.
Finding an objective measure of mental health that's been tracked reliably over time is a very difficult problem.
IMO Angus Deaton, the guy pushing the "deaths of despair" narrative, is cashing in his Nobel credibility to push an ideological narrative that is at best one of multiple hypotheses consistent with the available evidence.
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