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Eli Lilly releases data for a new weight-loss drug to tackle obesity : Shots - Health News : NPR

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This drug is a true gamechanger

In the SURMOUNT-1 study, people who took the highest dose of tirzepatide, most of whom had a BMI of about 30 or higher but did not have diabetes, lost about 21% of their body weight during the 72 week study. As researchers point out, for people who have bariatric surgery, typical weight loss is about 25% to 30% of their weight, one or two years after the surgery. In the tirzepatide study, 36% of people taking the highest dose lost 25% or more of their body weight.

this is comparable to bariatric surgery

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You don't have to be a whale to be a regular customer. A Big Mac, a small serving of fries and a diet soda is a perfectly cromulent lunch. A bit high in fats and tastes like nothing, but generally fine if you're an office worker. Hell, you can have the same setup for dinner and an Egg McMuffin Meal for breakfast and you'll be fine as a "thrice a day customer".

Of course, upgrading to medium fries adds 90 Cal per serving, a single packet of ranch is 110 Cal more, a small soda is 150 Cal, boom, you're eating 700 extra calories and putting on weight without being a "whale" that eats ten burgers every day. And that's without any other snacks and creamy sugary coffees the same person might have throughout the day.