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greyenlightenment  investments: META/FBL, TSLA, TQQQ, TECL, MSFT ...  1yr ago (npr.org)   2624 thread views

Eli Lilly releases data for a new weight-loss drug to tackle obesity : Shots - Health News : NPR

npr.org

This drug is a true gamechanger

In the SURMOUNT-1 study, people who took the highest dose of tirzepatide, most of whom had a BMI of about 30 or higher but did not have diabetes, lost about 21% of their body weight during the 72 week study. As researchers point out, for people who have bariatric surgery, typical weight loss is about 25% to 30% of their weight, one or two years after the surgery. In the tirzepatide study, 36% of people taking the highest dose lost 25% or more of their body weight.

this is comparable to bariatric surgery

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Down Syndrome is tolerated even though it can be prevented with prenatal screening.

Statements like this really make you appreciate how hard AI alignment will be. We can't even get humans to reliably differentiate between "prevent illness" and "kill sick people and replace them with healthy people".

Down Syndrome people aren't 'sick'. Having Down Syndrome is their default state. It's not a sickness, it's congenital.

Now, why are we equivocating between abortion and murder?

Alignment is easy. Agreement is hard. The Bailey is «aligning the AI to the generic mode of operation where it makes sure the user's intent is understood correctly and does not go all monkey's paw». The Motte is «having the AI align the future to your preference, very much not obliging the user when the instruction is against my preferences».

This is the general problem of politics.

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