The Wednesday Wellness threads are meant to encourage users to ask for and provide advice and motivation to improve their lives. It isn't intended as a 'containment thread' and any content which could go here could instead be posted in its own thread. You could post:
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Requests for advice and / or encouragement. On basically any topic and for any scale of problem.
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Updates to let us know how you are doing. This provides valuable feedback on past advice / encouragement and will hopefully make people feel a little more motivated to follow through. If you want to be reminded to post your update, see the post titled 'update reminders', below.
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Advice. This can be in response to a request for advice or just something that you think could be generally useful for many people here.
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Encouragement. Probably best directed at specific users, but if you feel like just encouraging people in general I don't think anyone is going to object. I don't think I really need to say this, but just to be clear; encouragement should have a generally positive tone and not shame people (if people feel that shame might be an effective tool for motivating people, please discuss this so we can form a group consensus on how to use it rather than just trying it).
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Notes -
Does anyone use NMN or NR supplements for prevention of aging? After reading "Lifespan" by David Sinclair I've been supplementing with NMN for the last 2 or 3 years using Toniiq NMN supplements.
This decision has proved somewhat complicated. For one, many NMN supplements are frauds that contain no NMN at all (https://www.prohealth.com/blogs/press-releases/fake-fraudulent-nmn-products-on-amazon-exposed). Toniiq seems to be decent, but that just means it could work. Lots has to go right here for this to happen. The NMN has to be absorved. It has to turn into NAD+ in my body. And NAD+ has to actually do something.
So far, I'm down a few hundred bucks and I can say confidently that I've felt zero effects positive or negative from NMN.
Meanwhile, the people who are pushing NMN (David Sinclair) and NR (Charles Brenner) seem to have somewhat questionable ethics - both having received millions of dollars from supplement companies (Elysium in the case of Dr. Sinclair, and TruNiagen in the case of Dr. Brenner). They also apparently hate each other.
We get shit like this:
https://twitter.com/CharlesMBrenner/status/1642378345127227393
In the fog of war, I don't know what to think. Is one man a fraud? Are both men frauds? It reminds me of the debates over Ivermectin. The ground becomes so muddied there's no clear way forward. Where is Scott when you need him to write a 10,000 word essay on the subject?
In any case, much like Ivermectin, the null hypothesis would be that NMN doesn't do shit. But the testimonials of Dr. Sinclair in "Lifespan", especially in regards to his father, were so strong I want to believe.
I'm just going to piggyback off this to make my own supplement statement. Being a basic bitch, I listen to the Huberman Lab, and I decided to get the "Hormone Support" bundle from Momentous, more out of a sense of wanting to support the podcast than anything. I've used random supplements reported to boost testosterone on sporadic occasions, but never noticed much difference.
Since taking it, I've definitely noticed a mild difference. I've bulked up some, and put on a good amount of muscle, even though my diet and sleep has been all out of whack for personal reasons, and my workouts haven't been great either. It feels like I'm getting more out of this than I should. I'm thinking in the future I plan to buy any supplements I want to take from them, maybe the problem all along has been using supplements that don't actually contain supplements.
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