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I didn't ask for an estimate, I asked why 1 per 1 million is the higher tolerable level of risk.
Why does it being a year old matter? Even if the IFR is a few times lower, it's still much, much, much higher than what you're talking about.
Do you plan on explaining why or are you just going to make assertions?
It's entirely possible to build towns and cities that don't require you to drive literally everywhere, but no one seems to care about the risk from driving when designing cities or choosing where to live. At least, not at the magnitude you're talking about: 100 miles could be saved in 2 months by moving 1 mile closer to work, but does anyone care about that? Not in the slightest. A minuscule improvement in civil design would save orders of magnitude more lives than eliminating all risk from vaccines, with lots of other positive side effects to boot.
This entire post of yours is just one big isolated demand for rigor.
1 in one million, compared to 1 in 100,000, in our current data collection environment, is a good signal to keep track of if you are considering your options to receive a covid-19 vaccine. Perhaps you can take J&J, Novavax, or Covaxin and maintain protection against SARS-2.
The IFR is lower and vaccines are not denting hospitalization or death rates as they plummet from their previous heights (mass naïve infection). Most people have had a much better inoculation than a monovalent vaccine - they've had a SARS-2 infection.
Well, because a stroke as a cardiovascular event, I'm interested in the dynamic between mRNA vaccination and your cardiovascular system. A stroke, downstream of pathology, will offer valuable information when it goes above the baseline.
Well, you are demanding rigor, and yet I feel like this is a complex claim. Even a city would involve having people driving to bring supplies and transportation towards these centers - a mandatory risk.
We should be paving our public serology with only the best, most well understood vaccines that we are capable of developing and testing and passing on in our limited lifetimes. There is a broader umbrella of rigor that I am requesting to be frank.
A lot of the rigor I'm demanding will also take time, more time than has been allotted for these Bivalent updates. The first injectable, multi-transcriptional (unknown if combined or separated) mRNA vaccine to market has shown an unexpected safety signal.
...why? What makes it a good signal? Again, compared to the baseline number of strokes, you probably would not ever be able to detect these increases. If you wouldn't seriously consider the risk of driving 1000 miles, why would you seriously consider this risk?
Do you have some data for these claims? I've seen them, but I've also seen the opposite (e.g. that vaccine provides a better immune response than previous infection). Case and hospitalization rates are certainly nowhere near their high of a year ago (https://www.cdc.gov/coronavirus/2019-ncov/covid-data/covidview/index.html) but if the virus is mutating to become more contagious and less severe over time, and vaccines aren't actually effective, you should still see a high case count.
What valuable information? How does this answer my question?
I'm not really sure what you are trying to say. There are plenty of alternatives to using large motor vehicles in city centers, near pedestrians. Also, deliveries of goods represent a tiny fraction of all trips taken in populated areas, so you can still have those while reducing personal car trips. Urban design is a complex topic, but so is medicine. Do you want me to recommend you some urbanist sources?
This seems like a much weaker conclusion than:
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