I was wondering wether the change is acute or durable if so how long.
Most importantly I am wondering how much the notion of limited/scarce lymphocyte T memory is true over longterm, AKA would a simulated vaccine infection recruit an excess amount of lymphocyte T and therefore accelerate functionally thymus involution/age immunosuppression and age immuno-inadaptativity.
As a reminder, lymphocyte T half life is 17.5 years.
Finally has anyone data/insights on the relevance of semi-chronic (how long) inflammation because of increased immune activity (including cytokines) by vaccines (and on oxidative stress) ?
Those are the questions that matter regarding the latent invisible (actually not) effects vaccines could have when we get old in 50 years.
Note:
No I'm not an antivaxx.
I have erudition in medecine but regarding those questions I am partially ignorant.
It is plausible the chronic very long term effects of those vaccines are negligible but still those questions needs to be answered, and to even begin, must be answered wether the vaccine has chronic effects at all, AKA at least one Biomarker that would be altered over a year? many years?
This is completely observable but the world is it seems, too mediocre to do said observation semi-exhaustively.
However even if the inflammation would be only acute (not a given), the fact it induce myocarditis shows that effect on health can be potent.
Therefore it doesn't take many braincells to understand that humans have varying health damage "budgets" and that on many, they would not have myocarditis, yet it could still plausibly induce long term microscopic conformational changes (mitochondria fitness, apoptosis or cellular sensecence) and other low observable latent accelerated ageing.
Again I believe a significant effect is unlikely, yet I also believe the medical system is too mediocre to fund the answers to those questions, let alone update policies based on said answers. One day, mankind will again play with dices, but this day, mankind will be doomed.
I hope we got lucky.
I hope someone will collaboratively take motivation to answer some of my important questions.
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Notes -
Can someone find a comparison of excess mortality between the vaccinated and the unvaccinated that is up to date?
I was skimming this study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012513/ that shows Interferon I signaling depletion induced by mRNA vaccines.
I was wondering wether the change is acute or durable if so how long.
Most importantly I am wondering how much the notion of limited/scarce lymphocyte T memory is true over longterm, AKA would a simulated vaccine infection recruit an excess amount of lymphocyte T and therefore accelerate functionally thymus involution/age immunosuppression and age immuno-inadaptativity.
As a reminder, lymphocyte T half life is 17.5 years.
Finally has anyone data/insights on the relevance of semi-chronic (how long) inflammation because of increased immune activity (including cytokines) by vaccines (and on oxidative stress) ?
Those are the questions that matter regarding the latent invisible (actually not) effects vaccines could have when we get old in 50 years.
Note:
No I'm not an antivaxx.
I have erudition in medecine but regarding those questions I am partially ignorant.
It is plausible the chronic very long term effects of those vaccines are negligible but still those questions needs to be answered, and to even begin, must be answered wether the vaccine has chronic effects at all, AKA at least one Biomarker that would be altered over a year? many years?
This is completely observable but the world is it seems, too mediocre to do said observation semi-exhaustively.
However even if the inflammation would be only acute (not a given), the fact it induce myocarditis shows that effect on health can be potent.
Therefore it doesn't take many braincells to understand that humans have varying health damage "budgets" and that on many, they would not have myocarditis, yet it could still plausibly induce long term microscopic conformational changes (mitochondria fitness, apoptosis or cellular sensecence) and other low observable latent accelerated ageing.
Again I believe a significant effect is unlikely, yet I also believe the medical system is too mediocre to fund the answers to those questions, let alone update policies based on said answers. One day, mankind will again play with dices, but this day, mankind will be doomed.
I hope we got lucky.
I hope someone will collaboratively take motivation to answer some of my important questions.
I am in good faith.
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