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Small-Scale Question Sunday for February 23, 2025

Do you have a dumb question that you're kind of embarrassed to ask in the main thread? Is there something you're just not sure about?

This is your opportunity to ask questions. No question too simple or too silly.

Culture war topics are accepted, and proposals for a better intro post are appreciated.

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This was a messy time. Ivermectin appeared to only work in the global south where people had a high parasite burden - when it worked it was saving lives by treatment of parasites which improved outcomes because less parasites.

The lab leak vs. natural is still hotly debated by knowledgeable and they actually gave good arguments on both sides that dont parse very well to laypeople.

Much of what you are complaining is also directionally incorrect, it's the media recruiting doctors, not the other way around.

Which part is directionally incorrect? Fauci funneling money for research of gain of function then hiding it and laying through his teeth to congress? Fauci colluding with scientists to retain media control of the narrative? Scientists directly involved or benefiting from the gain of function research releasing bogus papers with the sole purpose of creating FUD to deflect from the accurate information the same exact lab did experiments on these viruses. The absolutely bullshit assertion the fluorine cleavage site could have occurred naturally in that particular combination?

How about doctors careers being threatened for not going along with the party line about covid and its treatments? Maybe the fucking 1984 panopticon style control of media channels with Facebook/Reddit/Twitter and Youtube shadow banning people, shadow banning search terms. Those Orwellian fact checker boxes under posts? What else was directionally incorrect., having to use retard speak like "the virus of unknown origin" or videos literally getting murdered in the algorytm of youtube if you mention the word "news" and your channel isn't on the pre-approved list of "trust worthy" news networks.

I can tell you ivermectin literally works by making the cells inner PH less conductive to fully forming the viral capsid.

Research indicates that ivermectin can inhibit the replication of SARS-CoV-2 in cell cultures, with a single treatment able to reduce virus levels by about 5000-fold at 48 hours post-infection

https://www.sciencedirect.com/science/article/pii/S0166354220302011

I can tell you ivermectin literally works by making the cells inner PH less conductive to fully forming the viral capsid.

How often have we cured cancer in a lab but when you apply the thing to real life clinical practice it isn't helpful?

It's nearly all the time, in fact it's the majority of medical research.

I can tell you the same mechanism reduces viral viability with other viruses too, also just look at hydroxychloroquine, and niclosamide, same basic mechanism.

Look at the literature that came out later after everyone calmed down, even if it had some lab impacts it didn't seem to have a useful clinical impact.

It's probably at best very similar to Tamiflu.