The Wednesday Wellness threads are meant to encourage users to ask for and provide advice and motivation to improve their lives. It isn't intended as a 'containment thread' and any content which could go here could instead be posted in its own thread. You could post:
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Requests for advice and / or encouragement. On basically any topic and for any scale of problem.
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Updates to let us know how you are doing. This provides valuable feedback on past advice / encouragement and will hopefully make people feel a little more motivated to follow through. If you want to be reminded to post your update, see the post titled 'update reminders', below.
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Advice. This can be in response to a request for advice or just something that you think could be generally useful for many people here.
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Encouragement. Probably best directed at specific users, but if you feel like just encouraging people in general I don't think anyone is going to object. I don't think I really need to say this, but just to be clear; encouragement should have a generally positive tone and not shame people (if people feel that shame might be an effective tool for motivating people, please discuss this so we can form a group consensus on how to use it rather than just trying it).
Jump in the discussion.
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Notes -
While I think your initiative is extremely laudable, just know that the path ahead of you is fraught. You may have a serious medical issue which forums could exacerbate. But keep documenting things, trying new things, and taking the initiative. I'd recommend a heavy bias towards experts who can see you in person, even if you have to shop around for the ones that work for you. Cautionary note: cascades of care, and incidentalomas.
Lastly, this reads like you're looking for a simple fix that has a clear mechanistic explanation. Generally speaking, I would not expect such specificity, but keep trying to make things better.
So, here is a layman speculation (without knowing your age, weight:height, mood, stability, aerobic capacity etc).
This sounds like anhedonia. It could be hormones (testosterone, free-T, T:E ratio, various thyroid hormones, medications you are taking, cortisol, micro or macro nutrient deficiency). These can all be looked at in one blood panel. I'd start with a full workup from a GP. (and the results will give us amateurs more to (possibly dangerously) speculate about!)
It may be a neurotransmitter imbalance. This can be an appealing thought, as it seems to promise a clear mechanistic solution. IME, it isn't nearly so cut and dry. If you can get through your day without chaos, I'd investigate this last.
For now:
Consider cutting caffeine. It isolates one variable and should improve sleep. I won't sugar coat this, this is awful for a week or two. However, you'll get back good data quickly. Sleep is a miracle drug.
Consider following a balanced diet of whole foods with a tiny caloric surplus. Whole foods and sufficient calories are the goal.
Supplements: vit-D+k, zinc, and magnesium are the most common deficiencies. Might want to wait until after the blood panel. Creatine 5g per day because almost no harm, many potential benefits. L-citrulline (malate is fine). May improve blood flow at 10g per day. Glycine for sleep. NAC works for some to clear brain fog. Can also allegedly cause anhedonia (did neither for me). Prob some others but the supplement world is waaaay overhyped imo.
One-crazy-thing: Carnivore diet. Never tried it. Seems insane. The good: It's simple (but not easy) to adhere to. It's an elimination diet so fewer variables. Its radically not the same, perhaps resulting in different outcomes. Wide anecdotal support. The bad: most support is anecdotal. Its wild. Diarrhea for a week.
Again: have a bias towards experts in person, but keep the initiative. Its your life you're free to experiment and deviate. Best of luck.
I've had this problem for a full decade now, so I've tried all the things you mentioned. Did carnivore, ingested a weird chemical powder from China, got blood work, etc. If none of that works, you're left alone to theorycraft some possible cause. Hence the post
Oooof. That's rough. Yeah, I'd say you're at the theorycraft stage. Add some info to your post. I'm still unsure exactly what your symptoms are, how they present, your clinical history, and current status.
I'm stumped, and this is way beyond my pay grade anyhow. I perused the "The Mechanical Basis of ME/CFS" post. Interesting stuff from deep down a rabbit hole. And from your other comments its seems like you know how things work. Best of luck!
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