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Wellness Wednesday for May 10, 2023

The Wednesday Wellness threads are meant to encourage users to ask for and provide advice and motivation to improve their lives. It isn't intended as a 'containment thread' and any content which could go here could instead be posted in its own thread. You could post:

  • Requests for advice and / or encouragement. On basically any topic and for any scale of problem.

  • Updates to let us know how you are doing. This provides valuable feedback on past advice / encouragement and will hopefully make people feel a little more motivated to follow through. If you want to be reminded to post your update, see the post titled 'update reminders', below.

  • Advice. This can be in response to a request for advice or just something that you think could be generally useful for many people here.

  • Encouragement. Probably best directed at specific users, but if you feel like just encouraging people in general I don't think anyone is going to object. I don't think I really need to say this, but just to be clear; encouragement should have a generally positive tone and not shame people (if people feel that shame might be an effective tool for motivating people, please discuss this so we can form a group consensus on how to use it rather than just trying it).

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Yeah semaglutide is making literally all the difference for me, but only through the "I'm much less hungry" pathway, I don't think it has some special fat-burning ability outside of its appetite suppression, so if that hasn't historically been a problem for you, then semaglutide probably won't help.

How long did it take for things to "kick in"? I am starting with a different GLP-1 agonist and while the initial nausea has passed I don't feel like my appetite has dropped that much.

It really took me like 6 weeks to see the full effects. These have half-lives of about a week, which means that the concentration in your blood after a few weeks of taking it is actually twice as high as it was the first week. The initial weeks were also spent slowly escalating the dose to make sure I minimised side-effects. I'm taking 1.0mg/week of semaglutide spread into 2 injections each week, at this dose my appetite is very clearly suppressed, and I could already feel effects when my dosing was 0.6mg/week.