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Notes -
Vaccines have to be more good than bad. Almost all of them are. The covid vaccines get a wee bit murky in that regard when you get to younger age cohorts - especially younger male cohorts. There's a lot of good evidence that for young males in particular the virus carries fewer side effects than the mRNA vaccines, especially the 2nd dose of said vaccines. For older age groups I think you'd have to show pretty awful side effects for vaccination not to be worth it - so, for instance with over 65s you'd have to really have some bad frequency of side effects since they're so vulnerable to covid.
The other issue at hand here is efficacy, however. If the bivalent booster has risks but doesn't ultimately protect anyone any better than the 2x shots they already had (or 3x with the original booster) then there's really no good argument for them. The FDA lost two of its most experienced vaccine regulators over the Biden admin's "boosters for all" push, which wasn't based on any data whatsoever - we don't have any data showing that a 30 year old vaccinated woman will have further reduced mortality and morbidity with a booster shot or a bivalent booster. Most other countries, where their medical systems are more tuned towards cost and efficacy, have only authorized boosters for elderly people and those with severe immunocompromise (cancer patients). The US chose to push a one-size-fits-all policy with boosters, with zero evidence, and so...when a safety signal like this bubbles up it looks even worse than it would have if they'd pursued more evidence based recommendations.
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