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gulch  2yr ago (text post)   2581 thread views

Does NMN sound to good to be true?

So I recently heard about this supplement called Nicotinamide Mononucleotide. It's heralded as this great medicine that reduces aging, and gets rid of many issues.

And I really want to believe it, but there's something snakeoil salesmany about it.

  • It's heralded as a magical cure with no downside

  • It resolves so many issues and problems with your body it's unreal

  • From brain to liver, to ankles and skin, it's all covered

It all sounds too good to be true to me. I don't think it has negative effects and it's actually malicious, but I think it's just a fad that's being pushed. I don't think it can do really bad harm, but I don't think there's any better effects than a tummy ache.

What do you think? Do you have experience with this supplement?

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Only half-relevant, but is there any update on fisetin being the fountain of youth? It was shilled around here quite a bit a while back.

Some clinical trials on it are about to end soonish, so hopefully we'll know if it werks.

There's this one with end date specified as December 1st this year:

https://clinicaltrials.gov/ct2/show/NCT04210986?cond=fisetin&draw=2&rank=10

And the Mayo Clinic one, that's supposed to finish half a year from now:

https://clinicaltrials.gov/ct2/show/NCT03675724?cond=fisetin&draw=2&rank=4

I wonder how long it will take from the scheduled study completion time to actual publication of results.

fisetin

NMN is shilled harder.

Both of them have the adverse effects of 'slight tummy ache', although NMN is shown to actually restore vitality.

although NMN is shown to actually restore vitality.

Didn't fisetin do something like increase mouse lifespan by 20% when they started giving it at mouse middle age?

So in your opinion fisetin doesn't do much?

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