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Notes -
Random flu combinations is a yearly occurrence and something that is tracked by global public heath authorities. Also reminder that the flu is really fucking bad but we mostly forget about that because at risk persons are strongly incentivized to get flu shots.
Here's a link-
https://cdn.who.int/media/docs/default-source/wpro---documents/emergency/surveillance/avian-influenza/ai_20241025.pdf
It is worth noting that the type of flu most likely to result in human to human transmission does have a strong possibility of resulting in lower lethality.
However we've had presumed mammal to human transmission in the U.S. already, IIRC.
The problem is when it goes human to human (which it may not).
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