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PaperclipPerfector  25d ago (text post)   2848 thread views

Small-Scale Question Sunday for October 27, 2024

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A few years ago 4000 was the maximum daily dose but the FDA has recently revised the recommendation down to 2000 mg because of evidence that acetaminophen is more hepatotoxic that previously realized. And to reduce the risks of accidental overdose from multiple medications, and because of the synergistic damaging effects with alcohol.

I've got to ask again where you are getting those numbers from.

I googled fda.gov acetaminophen safety and the first result, explicitly labeled “current as of” February of this year, has the same number as the Harvard article I cited in the toplevel comment:

The current maximum recommended adult dose of acetaminophen is 4,000 milligrams per day

https://www.fda.gov/consumers/consumer-updates/dont-overuse-acetaminophen

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