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Notes -
Yes, that’s the case.
Because of the virulence of vaccina, the virus used to inoculate against smallpox, smallpox vaccines are more dangerous than most other kinds of immunizations. For example, I have chronic eczema, and so it would be a very bad idea for me to be vaccinated against smallpox — there’s a risk of vaccina infecting the skin and causing a major infection.
And it should be noted that we’re seeing a dramatic increase in eczema… so if there were to be a monkeypox pandemic, there’s a huge chunk of the population that couldn’t be safely inoculated with the old smallpox vaccine.
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