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Culture War Roundup for the week of August 5, 2024

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This is how we get hundred billion dollar black holes, massive financial crises, wars that go nowhere based on pure fantasy and defiance of reality, 20 years of barking up the wrong tree on Alzheimers research due to fraud...

Where did you read that take? It's not clear to me whether you mean Marc Tessier-Lavigne or Sylvain Lesne, but in both cases it's a huge overstatement. Both were peripheral to the main story of beta-amyloid plaques which originated before either author, had strong evidence in favor of it, and (I would argue) have strong evidence in favor of the plaque hypothesis being false at this point. But the enormous research and clinical efforts on beta-amyloid plaques would have happened even in the absence of either fraud.

I'll note that of the people in the field I've spoken with, most still believe in the plaque hypothesis and think we just aren't treating patients early enough or some other excuse.